The Best Antibiotics for a Prepper’s Emergency Supply

Finally, you can get antibiotics for emergency storage. Everyone needs a medicine plan for emergencies, and one of the main battles when storing antibiotics is simply getting them. Getting FDA-approved antibiotics requires you to have a prescription, which is thankfully much easier now with TeleDocs. With a quick video call, prepper antibiotics issues are in the past.

There are a few options to consider when it comes to antibiotics for prepping long-term medical storage: value, antibiotic type, ease of obtaining, etc. This is where we come in. We’ve researched the best antibiotics, and now the results are in: the overall best, a budget option, and an option for pets. If you need antibiotics that will help you stock your medical kit, one of our picks will help fill it.

Contents (Jump to a Section)

Jase Medical Antibiotics Case

The Best Antibiotics

Jase Case

Easy, Inexpensive, and Good Shelf Life

Disrupting the medical industry by making antibiotics available without all the red tape.

*Price at time of publishing; check for price changes or sales.

Jase Medical has changed the game. Gone are the days of squirreling away antibiotics like contraband, they’ve actually managed to make getting antibiotics easy and relatively cheap! Included in their fancy case with accompanying guide are:

  • Amoxicillin-clavulanate 875 mg: 28 tablets
  • Azithromycin 250 mg: 6 tablets
  • Ciprofloxacin 500 mg: 28 tablets
  • Doxycycline 100 mg: 120 capsules
  • Metronidazole 500 mg: 30 tablets

The kit bag is sturdy and has plenty of room inside. The color is nice as it distinguishes antibiotics from traditional red first aid pouches. If you keep the antibiotics in a cool, dry environment they can keep for long past their printed expiration (over 5 years). The one limitation with Jase is that they only allow one order per year, per person. So, get your order in quickly if you need a larger stock so you can order again in one year’s time.

With a solid kit and a price that doesn’t break the bank, the Jase Case has changed prepper antibiotics forever.

Traditional Prescriptions

Budget Antibiotics

Traditional Prescriptions

Easy, Insurance-Covered, and Common Sense

Leftover antibiotics prescriptions don’t need to meet the trash can if you store them properly.

We know… pharmacies are not fun. But if your insurance copay gets you some antibiotics for a few bucks, this is definitely the cheapest option. The problem is- you can’t get antibiotics from a typical pharmacy until your doctor insists that you need them. Then they write up a prescription for you, you have to make the PITA visit to the pharmacy and wait around for it to fill.

Sometimes, you may not use all of the antibiotics. Depending on your infection, you might end up with spares. Usually, you are instructed to throw away any remaining but the shelf life can be pretty good on them. You can make a judgment call on whether it’s worth storing in a cool dark environment to preserve its shelf life.

Obviously, if you don’t have any antibiotics in storage and you need them now then you are back to square one, but it’s worth keeping in mind the next time you get some from the pharmacy.

Vet Fish and Bird Antibiotics

Vet Antibiotics


Non-FDA Approved, Not Cheap, and Meant for Fish

Hoarded for years by preppers, this is no longer the only option to get antibiotics in your preps.

*Price at time of publishing; check for price changes or sales.

The Fish Mox family has had a name change, and now ‘Fish’ is replaced with ‘Aqua’. It’s probably because these antibiotics aren’t just for fish. You can use them on birds and a few other aquatic creatures. They match up to antibiotics you may recognize right on the front of their label, but they are not for human consumption. Here is what is printed on the labels:

  • Aqua-Mox (was Fish Mox) = Amoxicillin 500mg
  • Aqua-Ceph (was Fish Flex Forte) = Cephalexin 500mg
  • Aqua-Cipro (was Fin Flox)  = Ciprofloxacin 500mg
  • Aqua-Zole (was Fish Zole) = Metronidazole 500mg
  • Aqua-Zithro = Azithromycin

Luckily, preppers these days don’t hoard these. Getting antibiotics for human use is much easier, and all of these can now be left to the pets.

Everything We Recommend

Jase Medical Antibiotics Kit

Jase Medical

Disrupting the medical industry by making antibiotics available without all the red tape.

Where to Buy

$259* at Jase Medical

*at time of reviewing

Traditional Prescription Antibiotics

Traditional Prescription

Leftover antibiotics prescriptions don’t need to meet the trash can if you store them properly.

Where to Buy

Walmart Pharmacy

or your local pharmacy

Vet Fish and Bird Aqua-Mox Antibiotics


Hoarded for years by preppers, this is no longer the only option to get antibiotics in your preps.

Where to Buy

$234* at Heartland Vet Supply

*at time of reviewing

The Antibiotics We Compared

Our research narrowed the field down to the several antibiotics that we reviewed: Jase, Duration Health, traditional prescriptions, Aqua-Mox, Fish Mox, and more.

You can see our full list of review criteria below in the what to look for section, with an explanation for each.

We focused on antibiotic tablets and capsules. We excluded topical antibiotics and antiseptics. Those are definitely useful for first aid kits and prepping, but address different issues than oral antibiotics.

We’re always looking for new and better medical strategies, so if you have an antibiotic brand or supplier that you swear by let us know in the comments. We review most of our roundups annually, so we can always try to pick some up for the next roundup round and see if they make the cut and we can see if they will beat out our top picks.

What to Look For

The best prepper antibiotics for long-term medical storage have several important features to look for:

  1. Value
  2. Antibiotic Type
  3. Ease of Obtaining
  4. Size & Weight
  5. Shelf Life

When you get the right blend of these, you can find a reliable antibiotics that will help you treat a variety of infections and ailments. Below, we break down what each of these features means for the antibiotic brands and suppliers that set themselves apart.

Value: Cost vs. Benefit

The amount of money you spend on something like antibiotics shouldn’t blow out your entire budget. This might be tough if you do not have insurance and are getting a prescription filled.

On the flip side, you don’t want to go too cheap or just plain get the wrong thing. There is no reason to resort to fish antibiotics, homeopathic solutions, or anything else now that antibiotics are readily available to store for emergency use.

You never want to spend too much money on one resource, especially something like antibiotics. While antibiotics are a hot commodity during disasters and emergencies, it’s better to diversify your preparedness equipment to make sure you are covered for a wide range of scenarios. There is a sweet spot where you get high value with not-to-high of a price, which is where our top pick sits.

Antibiotic Type

There are many, many types of antibiotics that are useful for targeting specific bacterial infections. Most of these fall into families, with the main families being:

  • Penicillins – include phenoxymethylpenicillin, flucloxacillin, and amoxicillin
  • Cephalosporins – include cefaclor, cefadroxil, cefalexin
  • Tetracyclines – include tetracycline, doxycycline, and lymecycline
  • Aminoglycosides – include gentamicin and tobramycin
  • Macrolides – include erythromycin, azithromycin, and clarithromycin
  • Sulfonamides – include co-trimoxazole
  • Quinolones – include ciprofloxacin, levofloxacin, and norfloxacin

Some bacteria that cause infections (like MRSA) have become resistant to a wide range of antibiotics, while others have resistance to specific antibiotics.

Inappropriate use of antibiotics can contribute to these resistances, which is why antibiotics are prescription-only in most of the world.

Ease of Obtaining

Our top pick wasn’t even an option a few years ago. To get antibiotics for emergency storage, you’d have to get a little creative. Thankfully that’s no longer the case and antibiotics are easier than ever to store.

Doctors are increasingly concerned by bacterial resistance to antibiotics, so it is understandable why antibiotics are controlled behind the counter across most of the world. As long as you understand that you should only use antibiotics under a doctor’s direction, you won’t be contributing to the problem.

Size & Weight

If you are taking your prepper antibiotics kit to go in a portable first aid kit, you don’t need an entire pharmacy. Survival kits are optimized to have the lowest weight because you never know when an emergency situation will require you to hoof it long distances.

Shelf Life

Antibiotics in portable kits may degrade fast, so you’ll need to watch the tags for shelf life. Store them in a cool and dry spot and they’ll last year though. I prefer to keep them out of reach of kids (of course) and in a cool spot so I won’t have to cycle them out until at least 5 years from now.

Are Fish Antibiotics Safe for Humans?

No, it is not safe to take fish antibiotics. While you may have historically seen prepping sites compare various antibiotics with fish versions, there are a few major issues. Fish antibiotics are manufactured without regard for safety and health, unlike regular antibiotics, and are not FDA-approved, and sometimes are not even lab-grade.

Just because there are equivalencies between fish antibiotics and what your doctor prescribes doesn’t mean you should self-administer. In a wild SHTF scenario, you might consider it- but why would you have fish antibiotics laying around but not an easily-obtained antibiotic kit?

The days of fish antibiotics for prepper emergencies are behind us.

Who Needs Emergency Antibiotics?

Antibiotics are an essential part of a survival first aid kit, and those are essential in almost every in-place and mobile survival kit.

At the very least you should have them in your home as part of your in-place first aid kit:

Luckily, they are not as hard to come by anymore. On rare occasions, some people have allergic reactions to antibiotics so you should check with your doctor before adding prepper antibiotics to your kits on hand (if you haven’t already).

How We Review Products: We research thoroughly before selecting the best products to review. We consult experts in the field for a better understanding of what makes the gear great. Hours on end are spent field testing gear in stressful conditions. We assign performance criteria and impartially rate each tested item. You can support us through our independently chosen links, which can earn us a commission at no extra cost to you. After our review process, some of the items reviewed end up in our giveaways.

Sources and References

All of our experience and the testing we do to determine the best prepper antibiotics supplier is useless without listing our research sources and references. We leaned on these for the book knowledge that we paired with our hands-on testing and practical military and prepping experience:

Aminov, R. (2009). The role of antibiotics and antibiotic resistance in nature. Environmental Microbiology. Volume 11. Issue 12. Pages 2970-2988. (Source)

Mazer-Amirshahi, M., et al. (2017). Newly approved antibiotics and antibiotics reserved for resistant infections: Implications for emergency medicine. The American Journal of Emergency Medicine. Volume 35. Issue 1. Pages 154-158. (Source)

Zang, W., et al. (2020). Online availability of fish antibiotics and documented intent for self-medication. PLoS ONE. Volume 15. Issue 9. (Source)

The Final Word

Having antibiotics on hand can literally be a lifesaver during an emergency or disaster. Supply chain disruption and power outages occur with most regional disasters and national catastrophes, and antibiotics will be tough to get. Don’t let an infection threaten your life.

Here are a few related articles our readers have also found helpful:

We presented quite a lot of information, but as always: if you have any questions let us know and we would be happy to help. Our research and testing found the Jase Case to be the best option given its value, included antibiotics, ease of obtaining, profile, and shelf life.

If you pick up one of our suggested prepper antibiotics kits- make sure you are familiar with them and know when to use them. Don’t contribute to bacterial antibiotic resistance and know the basics of which type of antibiotic is for specific infections.

Keep exploring, stay prepared, and be safe.

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The Best Prepper Antibiotics

Rusty Collins

I am an engineer by day, but a prepper 24/7. I am an Air Force veteran that developed emergency and disaster plans as an emergency manager and responded to many attacks and accidents as a HAZMAT technician. I have been exposed to deadly chemical agents, responded to biological incidents, and dealt with natural disasters worldwide. Check out my full story here: Rusty's Story

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